Background and Objective: This study was conducted to evaluate the de Novo aneurysm formation in the long-term follow-up of patients with clipped intracranial aneurysms.
Methods: A total of 459 patients underwent the clipping of ruptured cerebral aneurysms in our institution during 1997 -2008. Of them, 119 patients were available in good condition and agreed to undergo 64 detector row computed tomography (CT) angiography. In addition, 8 patients with subarachnoid hemorrhage (SAH) underwent CT angiography.
Results: The mean ± SD interval from surgery was 7.2±2.3 years for CT-angiography controlled patents.
De novo aneurysms were detected in 5 of 119 (4.5%) patients and 4 of 8 patients with new subarachnoid hemorrhage. A history of multiple aneurysms was associated with the de novo aneurysm formation (p< 0.001).Conclusion: The risk of the de novo aneurysm formation in patients with clipped aneurysm is significant in long term follow-up. CT-angiography can be used as a non-invasive method for detection of de novo aneurysms in these patients.
Copyright. In accordance with Bethesda Statement on Open Access Publishing (released June 20, 2003, available from: http://www.earlham.edu/~peters/fos/bethesda.htm), all works published in JIVR are open access and are immediately available to anyone on the website of the journal without cost. JIVR is an open-access journal distributed under the terms of the Creative Commons Attribution 3.0 License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.