Vafa Rahimi-Movaghar Ali Haghnegahdar Amin Niakan Aidin Omidvar Ehsan Barzideh Fahim Baghban Mohammad Jamali Navideh Mohebali Hamed Yazdanpanah Seyede Maryam Fallahi Mehdi Salimi Sotoudeh Mohammad Reza Sharifirad


There is no clear evidence that early decompression following spinal cord injury (SCI) improves neurologic outcome.

In this primary report for prospective, randomized clinical trial, 35 selected spinal cord injured patients with traumatic thoracolumbar spinal cord injury were randomly assigned to early surgery (before 24 hours); and late surgery (24–72 hours).

Seventeen patients were assigned to the early and 18 to the late surgery. Twenty-five patients (71.4%) were male. Mean age of patients was 34 ± 12 years old. The most common levels of SCI were L1, T12, and T11 in 34%, 29%, and 11%, respectively. Sixteen (62.5%) had complete SCI (American Spinal Injury Association Impaired Scale (AIS) A. Number of patients with AIS B, C, D and E were 6, 5, 4, and 4, respectively. Follow-up of patients showed AIS A, B, C, D, and E in 7, 12, 4, 5, and 6 patients, respectively.

One patient (3%) was deteriorated who was from the early surgery group. No change in neurologic deficit was seen in 12 patients (34%). Eighteen patients (52%) improved one AIS grade, 8 were early and 10 late surgery. Three patients (9%) improved two AIS grades all were early surgery. Not available follow-up data for one patient (3%). Only 3/7 patients with AIS A in early surgery had one AIS grade improvement. In late surgery, 6/9 patients with AIS A had just one AIS grade improvement. Mean duration of hospitalization for all SCI patients were 11 ± 10 days, which was 8 ± 8 days for early and 14±12 days for late surgery.

Complications were two deaths, one in early surgery because of pulmonary emboli. Second death was in late surgery with unknown etiology. Two cases had deep vein thrombosis in early surgery. In late surgery, three cases had cerebrospinal fluid leak, meningitis and wound infection. Number of patients was not enough for comparing two surgery groups. However, both early and late surgery groups had some improvement in almost half of SCI patients.


How to Cite
RAHIMI-MOVAGHAR, Vafa et al. Primary report for a randomized controlled trial of traumatic spinal cord injured patients from T1 to L1 - description of the surgical decompression in two groups of before 24 hours and 24 to 72 hours. Journal of Injury and Violence Research, [S.l.], v. 4, n. 3, dec. 2012. ISSN 2008-4072. Available at: <http://jivresearch.org/jivr/index.php/jivr/article/view/374>. Date accessed: 17 dec. 2017.
Randomized controlled trial, traumatic spinal cord injury, thoracolumbar, surgical decompression, time
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